Atopic dermatitis, often called eczema or atopic eczema is a very common itchy skin condition that usually occurs in childhood, as well as adult life.
Because atopic dermatitis can be long lasting, it is important to learn how to take care of the skin. Proper daily skin care is essential to control the condition and alleviate much of the discomfort.

The most important element in the prevention and management of atopic dermatitis is the hydration of dry and sensitive skin. The dryer the skin is, the more moisturizing is needed. Keeping skin soft and hydrated, the need of other therapies could be reduced.

Based on this fact, Rontis complemented the Novalou® range with the Novatopia® series of specialized products, designed for the holistic care of dry, sensitive and atopic skin*: By a similar mechanism to that of a probiotic, the innovative active ingredient of plant origin, Indufence®, stimulates and optimizes skin’s natural defenses.

*For atopic skin first consult a dermatologist

  • Apply a small quantity of novatopia emollient milk bath to wet skin and scalp and gently clean. Rinse off thoroughly and gently pat the skin. For optimal skin hydration, use in combination with novatopia emollient cream.
  • • Use after exposure to low temperature (e.g. winter sports)
    • Use after sun exposure (e.g. after sun)
    • Use in dry and dehydrated skin due to medicines (e.g. diuretics). Compatible with any medication
    • Management of senile itching
    • Make up remover
    • Stretch marks prevention (e.g. pregnancy)
  • 1. Moisturizing capacity of vegetal ceramides
    • +73% increase in hydration at 30 minutes
    • +53% increase in hydration at 8 hours
    Efficacy1
    Similar to skin ceramides, vegetal ceramides of rice provide a rapid moisturizing effect, as well as a long-lasting hydrating effect, improving the texture and structure of the skin.

    2. Strengthening of mechanical barrier – Natural peptides of Alisma Plantago (Indufence®)
    A chemical or microbial aggression leads to an alteration of the tight network of keratinocytes, which is involved in the maintenance of the skin barrier function. Tested at 0.50%, INDUFENCE® restores the formation of the tight junction network, previously altered by the chemical or microbial aggression.

    3. Strengthening of biological barrier – Natural peptides of Alisma Plantago (Indufence®)
    Tested at 1% on normal human keratinocytes, INDUFENCE® significantly stimulates the expression of TLR2, a key receptor of innate immunity, by 48%.

    4. Reduction of inflammation – Natural peptides of Alisma Plantago (Indufence®)
    Tested at 1% on normal human keratinocytes, INDUFENCE® significantly limits the production of IL-8 (protein responsible for the onset of inflammation), caused by a microbial aggression, by 33%.

    5. Effect of Indufence® on TEWL (Trans-Epidermal Water Loss) – Natural peptides of Alisma Plantago (Indufence®)
    INDUFENCE® at 3%, results in a significant decrease of TEWL, starting at 7 days and after 14 days of twice daily applications. This effect was observed in 75% of the volunteers. The effect of INDUFENCE® continues for 7 days after stopping application, with a significant decrease of TEWL compared to the placebo.

    • -12.3%, decrease of TEWL at 7 days
    • -14.4%, decrease of TEWL at 14 days
    • -9.9%, decrease of TEWL at 21 days (persistent effect)
    Efficacy5

    6. Skin quality - Smoothing effect (cheeks) – Natural peptides of Alisma Plantago (Indufence®)
    After 28 days of twice daily applications, roughness parameters Sa and Sq decreased in 65% and 71% of the volunteers, respectively.
  • Apply the novatopia emollient cream 2-3 times a day to dry skin and massage gently. For optimal skin hydration, use in combination with novatopia emollient milk bath.
  • • Use after exposure to low temperature (e.g. winter sports)
    • Use after sun exposure (e.g. after sun)
    • Use in dry and dehydrated skin due to medicines (e.g. diuretics). Compatible with any medication
    • Management of senile itching
    • Make up remover
    • Stretch marks prevention (e.g. pregnancy)
  • 1. Moisturizing capacity of vegetal ceramides
    • +73% increase in hydration at 30 minutes
    • +53% increase in hydration at 8 hours
    Efficacy1
    Similar to skin ceramides, vegetal ceramides of rice provide a rapid moisturizing effect, as well as a long-lasting hydrating effect, improving the texture and structure of the skin.

    2. Strengthening of mechanical barrier – Natural peptides of Alisma Plantago (Indufence®)
    A chemical or microbial aggression leads to an alteration of the tight network of keratinocytes, which is involved in the maintenance of the skin barrier function. Tested at 0.50%, INDUFENCE® restores the formation of the tight junction network, previously altered by the chemical or microbial aggression.

    3. Strengthening of biological barrier – Natural peptides of Alisma Plantago (Indufence®)
    Tested at 1% on normal human keratinocytes, INDUFENCE® significantly stimulates the expression of TLR2, a key receptor of innate immunity, by 48%.

    4. Reduction of inflammation – Natural peptides of Alisma Plantago (Indufence®)
    Tested at 1% on normal human keratinocytes, INDUFENCE® significantly limits the production of IL-8 (protein responsible for the onset of inflammation), caused by a microbial aggression, by 33%.

    5. Effect of Indufence® on TEWL (Trans-Epidermal Water Loss) – Natural peptides of Alisma Plantago (Indufence®)
    INDUFENCE® at 3%, results in a significant decrease of TEWL, starting at 7 days and after 14 days of twice daily applications. This effect was observed in 75% of the volunteers. The effect of INDUFENCE® continues for 7 days after stopping application, with a significant decrease of TEWL compared to the placebo.

    • -12.3%, decrease of TEWL at 7 days
    • -14.4%, decrease of TEWL at 14 days
    • -9.9%, decrease of TEWL at 21 days (persistent effect)
    Efficacy5

    6. Skin quality - Smoothing effect (cheeks) – Natural peptides of Alisma Plantago (Indufence®)
    After 28 days of twice daily applications, roughness parameters Sa and Sq decreased in 65% and 71% of the volunteers, respectively.
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